Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 3/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30521365 | 1.00 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL17859477 | 0.89 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL30626872 | 0.76 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL26264545 | 0.76 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL24603565 | 0.76 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL30521270 | 0.73 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL12596659 | 0.73 | RAB9A (0.44) | RAB9ASMN1; SMN2NPC1KDM4EHTT | |
| SCHEMBL30521643 | 0.72 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL25804847 | 0.72 | NPC1 (0.37) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL15001036 | 0.72 | RAB9A (0.57) | RAB9ASMN1; SMN2NPC1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125681-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |