SCHEMBL258057

SCHEMBL258057

CCCCc1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccc(CCCC)cc5)c5cc(C)ccc5C)cc4)cc3)cc2)c2cc(C)ccc2C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 8/20 0.42
HSD17B10 Q99714 2/20 0.41
TSHR P16473 1/20 0.41
SKP2 Q13309 1/20 0.41
HSD11B1 P28845 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
NISCH Q9Y2I1 1/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
POLB P06746 1/20 0.38
NFKB1 P19838 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1299652 0.96 RARB (0.41) RARBHSD17B10TSHRSKP2HSD11B1
SCHEMBL3952262 0.85 HSD11B1 (0.42) RARBHSD11B1NPC1TP53POLB
SCHEMBL12545132 0.84 SKP2 (0.45) HSD17B10SKP2CA1CA2CYP3A4
SCHEMBL15854768 0.84 SKP2 (0.35) RARBHSD17B10TSHRSKP2HSD11B1
SCHEMBL12227053 0.83 SKP2 (0.44) HSD17B10SKP2CA1CA2CYP3A4
SCHEMBL12779463 0.83 HSD11B1 (0.43) RARBHSD17B10TSHRSKP2HSD11B1
SCHEMBL14594234 0.82 RARB (0.50) RARBHSD17B10TSHRHSD11B1CA1
SCHEMBL258192 0.82 RARB (0.50) RARBHSD17B10TSHRHSD11B1CA1
SCHEMBL17702098 0.82 RARB (0.50) RARBHSD17B10TSHRHSD11B1CA1
SCHEMBL2607544 0.82 RARB (0.50) RARBHSD17B10TSHRHSD11B1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 605 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2270601-B1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER WITH A FLUORINATED POLYMER AND A CORE SHELL COMPONENT XEROX CORP (US) 2017-11-29 EP claimed
EP-2270600-B1 Core shell photoconductors XEROX CORP (US) 2017-04-19 EP claimed
US-9411251-B2 Photoconductor containing a charge transport layer having an arylamine hole transport material XEROX CORPORATION (US) 2016-08-09 US claimed
EP-2290452-B1 POSS melamine overcoated photoconductors XEROX CORP (US) 2016-06-01 EP claimed
US-20150037715-A1 PHOTOCONDUCTOR CONTAINING A CHARGE TRANSPORT LAYER HAVING AN ARYLAMINE HOLE TRANSPORT MATERIAL XEROX CORPORATION (US) 2015-02-05 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8465888-B2 Photoconductor undercoat layer XEROX CORPORATION (US) 2013-06-18 US claimed
US-8268520-B2 Polyalkylene glycol benzoate polytetrafluoroethylene containing photoconductors XEROX CORPORATION (US) 2012-09-18 US claimed
US-20120196216-A1 PHOTOCONDUCTOR UNDERCOAT LAYER XEROX CORPORATION (US) 2012-08-02 US claimed
US-20120129086-A1 PHOTOCONDUCTORS CONTAINING CHARGE TRANSPORTING POLYCARBONATES XEROX CORPORATION (US) 2012-05-24 US claimed
US-20070292789-A1 Polyphenyl ether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292791-A1 Polyphenyl thioether containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292787-A1 Flexible imaging member such as a belt including a photogenerating layer and a charge transport mixture of an antioxidant and a polyphenyl thioether that may contain phenoxy groups, e.g., 1-phenoxy-3-[[3-(phenylthio)phenyl]thio]benzene; increased surface hardness, wear resistance and solvent resistance XEROX CORPORATION 2007-12-20 US claimed
US-20070292785-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292782-A1 Polyphenyl ether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292793-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292790-A1 Polyphenyl thioether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292786-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292784-A1 Thiophosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed
US-20070292783-A1 Ether phosphate containing photoconductors XEROX CORPORATION 2007-12-20 US claimed