Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 8/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625359 | 0.81 | PIK3CA (0.41) | PIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL30521191 | 0.80 | JAK1 (0.40) | PIK3R1PIK3CA | |
| SCHEMBL25807230 | 0.76 | PIK3R1 (0.36) | PIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL30521559 | 0.76 | PIK3R1 (0.36) | PIK3R1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL30521605 | 0.76 | AGTR2 (0.40) | — | |
| SCHEMBL2625356 | 0.76 | POLB (0.34) | PIM1PIM2 | |
| SCHEMBL30520916 | 0.76 | POLB (0.34) | PIM1PIM2 | |
| SCHEMBL30521075 | 0.74 | KRAS (0.37) | — | |
| SCHEMBL25446045 | 0.70 | JAK1 (0.33) | — | |
| SCHEMBL31514682 | 0.68 | POLB (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125627-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LYNK PHARMACEUTICALS CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |