Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25040639 | 0.85 | ESR1 (0.45) | ESR1ESR2 | |
| SCHEMBL25040924 | 0.80 | ESR1 (0.50) | ESR1ESR2KDM4E | |
| SCHEMBL26060359 | 0.78 | ESR1 (0.49) | ESR1ESR2KDM4E | |
| SCHEMBL24755557 | 0.78 | ESR1 (0.49) | ESR1ESR2KDM4E | |
| SCHEMBL24680259 | 0.77 | ESR1 (0.48) | ESR1ESR2KMT2A | |
| SCHEMBL25642904 | 0.77 | ESR1 (0.38) | ESR1ESR2ARKMT2A | |
| SCHEMBL25079756 | 0.77 | ESR1 (0.48) | ESR1ESR2KDM4E | |
| SCHEMBL26502462 | 0.75 | ESR1 (0.49) | ESR1ESR2KDM4E | |
| SCHEMBL26719244 | 0.74 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL24791895 | 0.73 | ESR1 (0.47) | ESR1ESR2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125627-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | LYNK PHARMACEUTICALS CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |