Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25040924 | 0.85 | ESR1 (0.50) | ESR1ESR2BACE1KDM4ELMNA | |
| SCHEMBL24755557 | 0.83 | ESR1 (0.49) | ESR1ESR2BACE1KDM4ELMNA | |
| SCHEMBL27062915 | 0.83 | ESR1 (0.41) | ESR1ESR2BACE1KDM4EMAPK1 | |
| SCHEMBL27338820 | 0.83 | CYP1A2 (0.37) | ESR1ESR2BACE1 | |
| SCHEMBL25079756 | 0.82 | ESR1 (0.48) | ESR1ESR2BACE1KDM4ELMNA | |
| SCHEMBL24680259 | 0.82 | ESR1 (0.48) | ESR1ESR2BACE1MAPT | |
| SCHEMBL26502462 | 0.80 | ESR1 (0.49) | ESR1ESR2BACE1KDM4ELMNA | |
| SCHEMBL24175927 | 0.79 | ESR1 (0.39) | ESR1ESR2ALOX15 | |
| SCHEMBL25040639 | 0.78 | ESR1 (0.45) | ESR1ESR2BACE1 | |
| SCHEMBL25808804 | 0.78 | ESR1 (0.45) | ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | ESR1 806/4885ESR2 1552/4885BACE1 3546/4885 |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | ESR1 764/4885ESR2 887/4885BACE1 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.