Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808446 | 0.93 | USP28 (0.58) | USP28KDM1AKMT2ABRD4 | |
| SCHEMBL25809850 | 0.92 | USP28 (0.69) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25808447 | 0.92 | USP28 (0.59) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25808401 | 0.92 | USP28 (0.59) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25794117 | 0.90 | USP28 (0.59) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25808485 | 0.90 | USP28 (0.56) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25813861 | 0.90 | USP28 (0.56) | USP28KDM1AKMT2ABRD4 | |
| SCHEMBL25808402 | 0.89 | USP28 (0.54) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25808487 | 0.87 | USP28 (0.57) | USP28KDM1AKMT2ABRD4MEN1 | |
| SCHEMBL25795474 | 0.84 | USP28 (0.68) | USP28KDM1AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |