Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492821 | 1.00 | CHRNA7 (0.53) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL25810428 | 0.91 | CHRNA7 (0.43) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL30492874 | 0.91 | CHRNA7 (0.43) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL25298855 | 0.90 | CHRNA7 (0.43) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL31025994 | 0.90 | CHRNA7 (0.43) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL17843055 | 0.87 | CHRNA7 (0.58) | CHRNA7PTPN2NR1H4MAPTKDM4E | |
| SCHEMBL30492882 | 0.86 | CHRNA7 (0.40) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL25811795 | 0.86 | PTPN2 (0.40) | CHRNA7PTPN2NR1H4MAPTGAA | |
| SCHEMBL25809773 | 0.85 | HRH4 (0.43) | PTPN2MAPTGAALGMNKDM4E | |
| SCHEMBL31025983 | 0.84 | OGA (0.43) | CHRNA7PTPN2MAPTGAALGMN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |