Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298855 | 0.93 | CHRNA7 (0.43) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL31025994 | 0.93 | CHRNA7 (0.43) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL30492853 | 0.91 | PTPN2 (0.42) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL25301130 | 0.91 | PTPN2 (0.42) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL25810428 | 0.88 | CHRNA7 (0.43) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL25811797 | 0.88 | HDAC1 (0.43) | PTPN2CHRNA7MAPTKDM4ENR1H4 | |
| SCHEMBL30492874 | 0.88 | CHRNA7 (0.43) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL30492821 | 0.86 | CHRNA7 (0.53) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL25810390 | 0.86 | CHRNA7 (0.53) | PTPN2CHRNA7MAPTGAAKDM4E | |
| SCHEMBL25296886 | 0.85 | PTPN2 (0.40) | PTPN2CHRNA7MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |