Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25916296 | 0.72 | PARP1 (0.39) | DRD4PARP1PLGHTR2AERCC1 | |
| SCHEMBL9910973 | 0.68 | DRD4 (0.35) | DRD4PARP1MAPK11MAPK14PLG | |
| SCHEMBL17001834 | 0.67 | PARP1 (0.42) | DRD4PARP1PLGERCC1ERCC4 | |
| SCHEMBL22860618 | 0.66 | PARP1 (0.44) | PARP1PLGHTR2AHTR1F | |
| SCHEMBL17001816 | 0.66 | PARP1 (0.35) | PARP1PLGHTR2AERCC1ERCC4 | |
| SCHEMBL25280436 | 0.64 | POLB (0.54) | PARP1 | |
| SCHEMBL15431908 | 0.63 | HRH3 (0.39) | DRD4PARP1PLGHTR1F | |
| SCHEMBL5255708 | 0.63 | ADRA1A (0.51) | PLGHTR1F | |
| SCHEMBL19127856 | 0.62 | HTR1D (0.39) | DRD4PARP1MAPK11MAPK14PLG | |
| SCHEMBL15701567 | 0.61 | PLG (0.42) | DRD4PARP1MAPK11MAPK14PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133229-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |