Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31444155 | 0.83 | CRBN (0.68) | DDB1CRBN | |
| SCHEMBL31444175 | 0.83 | DDB1 (0.68) | DDB1CRBNSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31443826 | 0.83 | CRBN (0.68) | DDB1CRBN | |
| SCHEMBL21965925 | 0.82 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL21965930 | 0.82 | DDB1 (0.71) | DDB1CRBN | |
| SCHEMBL27285006 | 0.82 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL23816109 | 0.82 | CRBN (0.71) | DDB1CRBN | |
| SCHEMBL21965432 | 0.82 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL21965439 | 0.81 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL25167746 | 0.80 | DDB1 (0.68) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |