SCHEMBL31444175

SCHEMBL31444175

O=C1CCC(Oc2cccc(Br)c2)C(=O)N1

nearest known ligand 0.68

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 19/20 0.68
CRBN Q96SW2 19/20 0.68
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25810627 0.83 DDB1 (0.68) DDB1CRBNSLC6A2SLC6A4SLC6A3
SCHEMBL31444155 0.83 CRBN (0.68) DDB1CRBN
SCHEMBL31443826 0.83 CRBN (0.68) DDB1CRBN
SCHEMBL31312873 0.82 CRBN (0.71) DDB1CRBN
SCHEMBL21965432 0.82 CRBN (1.00) DDB1CRBN
SCHEMBL25167746 0.80 DDB1 (0.68) DDB1CRBN
SCHEMBL21966190 0.80 DDB1 (0.63) DDB1CRBN
SCHEMBL21967018 0.80 DDB1 (0.63) DDB1CRBN
SCHEMBL21965925 0.80 DDB1 (0.64) DDB1CRBN
SCHEMBL21965930 0.80 DDB1 (0.71) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096856-A1 COVALENT CEREBLON LIGANDS C4 THERAPEUTICS, INC. (US) 2025-05-08 WO disclosed