Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.73 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459725 | 0.84 | DDB1 (1.00) | DDB1CRBN | |
| SCHEMBL29348755 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL31068264 | 0.82 | DDB1 (0.56) | DDB1CRBN | |
| SCHEMBL30844006 | 0.78 | CRBN (0.51) | DDB1CRBN | |
| SCHEMBL31068300 | 0.77 | DDB1 (0.64) | DDB1CRBNPOLB | |
| SCHEMBL29348808 | 0.77 | DDB1 (0.64) | DDB1CRBNPOLB | |
| SCHEMBL24319159 | 0.77 | DDB1 (0.56) | DDB1CRBNPOLB | |
| SCHEMBL34472068 | 0.75 | CRBN (0.51) | DDB1CRBN | |
| SCHEMBL30937147 | 0.75 | CRBN (0.50) | DDB1CRBNPOLB | |
| SCHEMBL29898475 | 0.74 | CRBN (0.47) | DDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |