Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492815 | 1.00 | MEN1 (0.46) | MEN1KMT2AKDM4EPKMALDH1A1 | |
| SCHEMBL3132185 | 0.80 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL31025962 | 0.80 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL29504669 | 0.79 | KDM4E (0.51) | MEN1KMT2AKDM4EPKMALDH1A1 | |
| SCHEMBL14004197 | 0.76 | MAPK13 (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL17842741 | 0.76 | CHRNA7 (0.47) | MEN1KMT2AKDM4EPKMALDH1A1 | |
| SCHEMBL16370957 | 0.73 | MEN1 (0.47) | MEN1KMT2AKDM4EALDH1A1HCAR2 | |
| SCHEMBL29728017 | 0.70 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EPKMALDH1A1 | |
| SCHEMBL4908387 | 0.70 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EPKMALDH1A1 | |
| SCHEMBL8563062 | 0.70 | ALDH1A1 (0.56) | MEN1KMT2AKDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |