SCHEMBL25811125

SCHEMBL25811125

c1ccc(-c2ccc(N(c3ccc4nc(-c5ccccc5)oc4c3)c3ccc4nc(-c5ccccc5)oc4c3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GPR119 Q8TDV5 10/20 0.50
KDM4E B2RXH2 2/20 0.50
HPGD P15428 2/20 0.50
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
GLA P06280 1/20 0.50
GAA P10253 1/20 0.50
CASP3 P42574 3/20 0.49
SENP7 Q9BQF6 3/20 0.49
SENP6 Q9GZR1 3/20 0.49
SENP8 Q96LD8 2/20 0.49
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23387560 1.00 NPC1 (0.52) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL23667811 0.98 SMN1; SMN2 (0.51) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL23667672 0.98 SMN1; SMN2 (0.51) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL25811182 0.97 GPR119 (0.51) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL23667741 0.97 NPC1 (0.52) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL25811167 0.96 NPC1 (0.54) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL23667882 0.95 NPC1 (0.51) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL22791712 0.94 NPC1 (0.55) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL25811164 0.94 NPC1 (0.55) NPC1RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL23667720 0.93 SMN1; SMN2 (0.47) NPC1RAB9ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309339-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-20230309339-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-11706943-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
US-11706943-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
EP-4207947-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME Hodogaya Chemical Co., Ltd. (JP) 2023-07-05 EP disclosed
EP-3731599-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-05-03 EP disclosed