Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25811372 | 1.00 | JAK3 (0.43) | JAK3NAMPTEPHX2RECQLTSHR | |
| SCHEMBL15723383 | 1.00 | JAK3 (0.43) | JAK3NAMPTEPHX2RECQLTSHR | |
| SCHEMBL12385902 | 0.90 | KMT2A (0.46) | NAMPTEPHX2RECQLTSHRSMN1; SMN2 | |
| SCHEMBL25811371 | 0.90 | RECQL (0.49) | RECQLTSHRSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL25811370 | 0.90 | RECQL (0.49) | RECQLTSHRSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL25811264 | 0.88 | GRM5 (0.42) | JAK3NAMPTEPHX2TSHRSMN1; SMN2 | |
| SCHEMBL12449665 | 0.80 | MAPT (0.52) | RECQLTSHRSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL16254889 | 0.80 | MAPT (0.52) | RECQLTSHRSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL12636 | 0.80 | MAPT (0.52) | RECQLTSHRSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17546315 | 0.80 | EPHX2 (0.46) | EPHX2RECQLTSHRSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |