Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25810187 | 0.89 | PIK3CD (0.45) | GRM5PIK3CDKMT2ACHRNB2CHRNA3 | |
| SCHEMBL25811311 | 0.88 | JAK3 (0.43) | CNR2JAK3NAMPTEPHX2PIK3CD | |
| SCHEMBL25811372 | 0.88 | JAK3 (0.43) | CNR2JAK3NAMPTEPHX2PIK3CD | |
| SCHEMBL15723383 | 0.88 | JAK3 (0.43) | CNR2JAK3NAMPTEPHX2PIK3CD | |
| SCHEMBL12385902 | 0.84 | KMT2A (0.46) | CNR2NAMPTEPHX2KMT2ATSHR | |
| SCHEMBL21216521 | 0.82 | EPHX2 (0.39) | GRM5CNR2JAK3RIPK1NAMPT | |
| SCHEMBL26649932 | 0.81 | RIPK1 (0.40) | GRM5CNR2RIPK1NAMPTEPHX2 | |
| SCHEMBL1978927 | 0.79 | CHRNB2 (0.65) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL10140410 | 0.78 | CHRNB2 (0.56) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL13013114 | 0.77 | HPGD (0.57) | CNR2NAMPTEPHX2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125737-A1 | HETEROCYCLIC COMPOUNDS AND USE THEREOF | SILEXON AI TECHNOLOGY CO., LTD. (CN) | 2023-07-06 | — | — | WO | disclosed |