Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.41 |
| ▸ | CTSS | P25774 | 8/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512445 | 0.79 | MEN1 (0.40) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL76832 | 0.79 | KDM4C (0.41) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL25229366 | 0.79 | MEN1 (0.44) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL8144616 | 0.77 | MEN1 (0.39) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL21834933 | 0.77 | KDM4C (0.39) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL16296168 | 0.77 | KDM4C (0.39) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL1234633 | 0.76 | CA1 (0.42) | CTSKMEN1GAAKMT2ATDP1 | |
| SCHEMBL22577405 | 0.76 | MEN1 (0.38) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL13744302 | 0.76 | MEN1 (0.38) | CTSKCTSSCTSLCTSBMEN1 | |
| SCHEMBL20776954 | 0.76 | MEN1 (0.38) | CTSKCTSSCTSLCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129667-A1 | PYRAZINE COMPOUNDS AS INHIBITORS OF FLT3 | BIOMEA FUSION, INC. (US) | 2023-07-06 | — | — | WO | disclosed |