Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22045503 | 1.00 | MEN1 (0.38) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL76832 | 0.77 | KDM4C (0.41) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL25229366 | 0.77 | MEN1 (0.44) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL2512445 | 0.77 | MEN1 (0.40) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL19373021 | 0.76 | DGAT1 (0.35) | MEN1GAAKMT2ATDP1DGAT1 | |
| SCHEMBL25811478 | 0.76 | CTSK (0.41) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL21834933 | 0.76 | KDM4C (0.39) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL8144616 | 0.76 | MEN1 (0.39) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL16296168 | 0.76 | KDM4C (0.39) | MEN1GAAKMT2ACTSSCTSK | |
| SCHEMBL22577405 | 0.74 | MEN1 (0.38) | MEN1GAAKMT2ACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098901-A1 | 3,8-DIAMINOTETRAHYDROQUINOLINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2009-08-13 | — | — | WO | disclosed |