Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25298308 | 0.89 | CHRNA7 (0.43) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL25811795 | 0.88 | PTPN2 (0.40) | CHRNA7ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL17843055 | 0.85 | CHRNA7 (0.58) | HDAC1CHRNA7ALDH1A1HPGDMAPT | |
| SCHEMBL25301143 | 0.82 | CHRNA7 (0.47) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL31025994 | 0.81 | CHRNA7 (0.43) | CHRNA7ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL25298855 | 0.81 | CHRNA7 (0.43) | CHRNA7ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL17858497 | 0.80 | HDAC1 (0.46) | HDAC1CHRNA7ALDH1A1HPGDMAPT | |
| SCHEMBL17858381 | 0.80 | MAPT (0.49) | HDAC1ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL25297616 | 0.79 | BCL2L1 (0.46) | HDAC1CHRNA7HDAC3HDAC4HDAC7 | |
| SCHEMBL30492853 | 0.78 | PTPN2 (0.42) | HDAC1CHRNA7ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |