Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 0.41 |
| ▸ | GSK3B | P49841 | 9/20 | 0.41 |
| ▸ | TTK | P33981 | 5/20 | 0.38 |
| ▸ | WNT1 | P04628 | 5/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.35 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497105 | 1.00 | DYRK1A (0.41) | DYRK1AGSK3BTTKWNT1CCNA2 | |
| SCHEMBL25301269 | 0.90 | DYRK1A (0.40) | DYRK1AGSK3BTTKWNT1CCNA2 | |
| SCHEMBL25301266 | 0.90 | DYRK1A (0.40) | DYRK1AGSK3BTTKWNT1CCNA2 | |
| SCHEMBL25813252 | 0.87 | DYRK1A (0.42) | DYRK1AGSK3BTTKWNT1LRRK2 | |
| SCHEMBL25813284 | 0.86 | MEN1 (0.40) | — | |
| SCHEMBL30497151 | 0.86 | MEN1 (0.40) | — | |
| SCHEMBL25813277 | 0.86 | MEN1 (0.40) | — | |
| SCHEMBL30497149 | 0.86 | MEN1 (0.40) | — | |
| SCHEMBL30497210 | 0.83 | KIFC1 (0.44) | — | |
| SCHEMBL30497138 | 0.83 | KIFC1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |