Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585420 | 0.87 | ALDH1A1 (0.51) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL4501755 | 0.87 | ACE (0.46) | ALDH1A1CTSKCTSSACE | |
| SCHEMBL4501759 | 0.87 | ACE (0.46) | ALDH1A1CTSKCTSSACE | |
| SCHEMBL2578532 | 0.86 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2588065 | 0.84 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2346620 | 0.84 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2346622 | 0.84 | ALDH1A1 (0.50) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2587761 | 0.84 | ALDH1A1 (0.52) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2345494 | 0.83 | ALDH1A1 (0.59) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2345486 | 0.83 | ALDH1A1 (0.59) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |