SCHEMBL25815330

SCHEMBL25815330

Cn1c(CN2CCC(c3cccc4c3O[C@H](c3nc5ccccc5s3)CO4)CC2)nc2ccc(C(=O)O)cc21

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 16/20 0.52
DRD2 P14416 1/20 0.52
DRD4 P21917 1/20 0.52
GRM2 Q14416 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815319 1.00 GLP1R (0.52) GLP1RDRD2DRD4GRM2
SCHEMBL25815948 0.93 DRD2 (0.50) GLP1RDRD2DRD4GRM2
SCHEMBL24186544 0.93 DRD2 (0.50) GLP1RDRD2DRD4GRM2
SCHEMBL24186509 0.89 GLP1R (0.56) GLP1R
SCHEMBL24186510 0.89 GLP1R (0.56) GLP1R
SCHEMBL24186507 0.89 GLP1R (0.56) GLP1R
SCHEMBL24186653 0.84 GLP1R (0.56) GLP1R
SCHEMBL24186422 0.84 GLP1R (0.56) GLP1R
SCHEMBL24186651 0.84 GLP1R (0.56) GLP1R
SCHEMBL25815512 0.84 GLP1R (0.56) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4209490-A1 FUSED IMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2023-07-12 EP disclosed