Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31363214 | 0.86 | KCNQ4 (0.38) | NPC1KCNQ4KCNQ5MAPTCA1 | |
| SCHEMBL31363319 | 0.86 | PLK1 (0.39) | TSHRSMN1; SMN2HPGDKCNQ4KCNQ5 | |
| SCHEMBL4838149 | 0.83 | NOTUM (0.49) | NOTUMALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL31738374 | 0.83 | KCNQ4 (0.39) | SMN1; SMN2MAPK1KCNQ4KCNQ5MEN1 | |
| SCHEMBL30148761 | 0.83 | KCNQ4 (0.39) | KCNQ4KCNQ5 | |
| SCHEMBL31738257 | 0.83 | CA12 (0.44) | NOTUMALDH1A1KDM4EGAAHPGD | |
| SCHEMBL1624928 | 0.82 | NOTUM (0.48) | NOTUMALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL15180119 | 0.82 | ALDH1A1 (0.44) | NOTUMALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL23113822 | 0.82 | MEN1 (0.45) | ALDH1A1TSHRSMN1; SMN2KCNQ4KCNQ5 | |
| SCHEMBL9246608 | 0.82 | MAPK1 (0.42) | KDM4EMAPK1KCNQ4KCNQ5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |