Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21017039 | 0.79 | MAPT (0.34) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL18081458 | 0.78 | KDM4E (0.33) | KDM4ENSD2ALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL29134748 | 0.76 | KDM4E (0.43) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL23717462 | 0.75 | OPRK1 (0.34) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL19836557 | 0.75 | OPRK1 (0.32) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL25481645 | 0.75 | HTT (0.33) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL25152682 | 0.74 | HTT (0.32) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL25189727 | 0.74 | KDM1A (0.34) | KDM4ENSD2ALDH1A1MAPTHTT | |
| SCHEMBL17396066 | 0.71 | MAPT (0.51) | KDM4EALDH1A1MAPTHTT | |
| SCHEMBL29303237 | 0.71 | HTT (0.37) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133229-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |