Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | HLCS | P50747 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.30 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2580848 | 1.00 | ALDH1A1 (0.39) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL2579275 | 1.00 | ALDH1A1 (0.39) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL27349151 | 0.98 | ALDH1A1 (0.35) | ALDH1A1S1PR3HLCSEPHX1 | |
| SCHEMBL8532189 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL2734736 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL2683007 | 0.84 | — | — | |
| SCHEMBL2326236 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL11388793 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL2204763 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR | |
| SCHEMBL8537115 | 0.84 | ALDH1A1 (0.46) | ALDH1A1S1PR3HLCSEPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048832-B2 | 1,3 dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090181870-A1 | 1,3 DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-7541319-B2 | 1,3-dithiolane-2-thione additives for lubricants and fuels | CHEMTURA CORPORATION (US) | 2009-06-02 | — | — | US | disclosed |
| US-20060089273-A1 | 1,3-Dithiolane-2-thione additives for lubricants and fuels | LANXESS SOLUTIONS US INC. | 2006-04-27 | — | — | US | disclosed |