Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815904 | 0.82 | KDM1A (0.39) | KDM1AHDAC4POLBSLC6A4SLC6A3 | |
| SCHEMBL5969962 | 0.79 | HSD17B10 (0.43) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL15630930 | 0.79 | HSD17B10 (0.43) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL5969963 | 0.79 | HSD17B10 (0.43) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL5969960 | 0.79 | HSD17B10 (0.43) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL5969851 | 0.77 | HSD17B10 (0.42) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL5969854 | 0.77 | HSD17B10 (0.42) | KDM1ACYP3A4CYP1A2CYP2D6TSHR | |
| SCHEMBL20480715 | 0.72 | HTR1A (0.39) | PDE5AACHEHDAC4P2RX7ALDH1A1 | |
| SCHEMBL28908685 | 0.71 | TSHR (0.40) | CYP1A2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL23813107 | 0.71 | PDE5A (0.39) | PDE5ACYP1A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448363-B2 | Kinase inhibitors | VIDYA THERAPEUTICS, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| CN-115867346-B | Kinase inhibitors | GB005股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219923-A1 | KINASE INHIBITORS | VIDYA THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| EP-4157446-A1 | KINASE INHIBITORS | GB002, Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| CN-115867346-A | Kinase inhibitors | GB005股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12448363-B2 | Kinase inhibitors | BTK, ABL1, LYN | PDE5A 1596/4885KDM1A 925/4885CYP3A4 3687/4885 |
| US-20230219923-A1 | KINASE INHIBITORS | BTK, ABL1, LYN | PDE5A 1596/4885KDM1A 925/4885CYP3A4 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.