Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25816391 | 0.77 | MEN1 (0.51) | MAPTP2RX7L3MBTL1LMNATSHR | |
| SCHEMBL5202907 | 0.75 | MAPT (0.47) | MAPTHTTP2RX7SIGMAR1GRIN2D | |
| SCHEMBL21392344 | 0.72 | KDM4E (0.58) | MAPTP2RX7SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL23016004 | 0.71 | GAA (0.61) | MAPTP2RX7SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL11990469 | 0.71 | SLC6A2 (0.42) | MAPTHTTRAB9ANPC1ALDH1A1 | |
| SCHEMBL7634561 | 0.71 | GAA (0.61) | MAPTP2RX7SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL2087914 | 0.68 | MAPT (0.41) | MAPTHTTP2RX7SIGMAR1GRIN2D | |
| SCHEMBL13246644 | 0.68 | MAPK1 (0.46) | MAPTHTTRAB9ANPC1HPGD | |
| SCHEMBL82901 | 0.68 | BRD4 (0.54) | MAPTHPGD | |
| SCHEMBL20012240 | 0.67 | MAPT (0.38) | MAPTHTTP2RX7SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130043-A1 | MONOACYLGLYCEROL LIPASE INHIBITORS AND USE THEREOF FOR THE TREATMENT OF ANXIETY | PSY THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |