Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 6/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.32 |
| ▸ | PDE4A | P27815 | 5/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2587650 | 1.00 | P2RX7 (0.36) | P2RX7PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4514287 | 0.86 | HTT (0.33) | P2RX7 | |
| SCHEMBL4520831 | 0.86 | HTT (0.33) | P2RX7 | |
| SCHEMBL4514289 | 0.86 | HTT (0.33) | P2RX7 | |
| SCHEMBL2584743 | 0.76 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL2579829 | 0.75 | P2RX7 (0.36) | P2RX7ALDH1A1MGLL | |
| SCHEMBL3623316 | 0.75 | P2RX7 (0.36) | P2RX7ALDH1A1MGLL | |
| SCHEMBL5126234 | 0.75 | P2RX7 (0.36) | P2RX7ALDH1A1MGLL | |
| SCHEMBL3627713 | 0.75 | P2RX7 (0.36) | P2RX7ALDH1A1MGLL | |
| SCHEMBL2577904 | 0.75 | P2RX7 (0.33) | P2RX7ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |