Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | CD44 | P16070 | 2/20 | 0.39 |
| ▸ | PNMT | P11086 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25596828 | 0.91 | PNMT (0.44) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| SCHEMBL25600800 | 0.89 | HTR2C (0.51) | HTR2CHTR2AHTR2BPNMT | |
| SCHEMBL25592289 | 0.89 | BCHE (0.32) | HTR2C | |
| SCHEMBL25593006 | 0.81 | HTR2A (0.37) | HTR2CHTR2AHTR2BCD44PNMT | |
| SCHEMBL25596940 | 0.79 | HTR2A (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL25592009 | 0.72 | PNMT (0.42) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| SCHEMBL25591876 | 0.72 | PNMT (0.42) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| SCHEMBL25591877 | 0.70 | HTR2C (0.48) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| SCHEMBL25593008 | 0.69 | BCHE (0.32) | — | |
| SCHEMBL4419414 | 0.69 | CES1 (0.39) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |