Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25597203 | 0.87 | DRD3 (0.49) | HRH1DRD3RAB9ATSHR | |
| SCHEMBL25816757 | 0.81 | HRH1 (0.33) | HRH1DRD3 | |
| SCHEMBL25602212 | 0.79 | HRH1 (0.40) | HRH1DRD3 | |
| SCHEMBL25592128 | 0.78 | DRD3 (0.43) | HRH1DRD3TSHR | |
| SCHEMBL25593050 | 0.75 | HRH1 (0.46) | HRH1DRD3HRH3 | |
| SCHEMBL25597315 | 0.75 | HRH1 (0.39) | HRH1DRD3RAB9ATSHR | |
| SCHEMBL25592130 | 0.74 | CYP2D6 (0.36) | HRH1DRD3 | |
| SCHEMBL25600320 | 0.74 | HRH1 (0.45) | HRH1DRD3HRH3 | |
| SCHEMBL25593002 | 0.74 | PNMT (0.47) | HRH1DRD3 | |
| SCHEMBL25593258 | 0.73 | HRH3 (0.31) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |