SCHEMBL25817814

SCHEMBL25817814

CC1Cc2ccc3c(C4CCC(=O)NC4=O)noc3c2C1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 20/20 0.41
CRBN Q96SW2 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29324611 0.75 CRBN (0.58) DDB1CRBN
SCHEMBL31323586 0.75 DDB1 (0.49) DDB1CRBN
SCHEMBL23117078 0.75 CRBN (0.49) DDB1CRBN
SCHEMBL31443853 0.75 CRBN (0.49) DDB1CRBN
SCHEMBL24754429 0.74 DDB1 (0.47) DDB1CRBN
SCHEMBL31444139 0.73 DDB1 (0.46) DDB1CRBN
SCHEMBL24754425 0.73 DDB1 (0.46) DDB1CRBN
SCHEMBL31444106 0.72 CRBN (0.46) DDB1CRBN
SCHEMBL24303012 0.72 DDB1 (0.37) DDB1CRBN
SCHEMBL24302892 0.72 DDB1 (0.37) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125944-A1 COMPOUND CONTAINING HETEROCYCLIC RING 正大天晴药业集团股份有限公司 2023-07-06 WO disclosed