SCHEMBL29324611

SCHEMBL29324611

Nc1cccc2c(C3CCC(=O)NC3=O)noc12

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.58
DDB1 Q16531 16/20 0.58
BRD4 O60885 1/20 0.40
TNF P01375 1/20 0.40
IL1B P01584 1/20 0.40
TBXA2R P21731 1/20 0.40
IKZF1 Q13422 1/20 0.40
IKZF3 Q9UKT9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31443853 0.85 CRBN (0.49) CRBNDDB1
SCHEMBL31323586 0.85 DDB1 (0.49) CRBNDDB1
SCHEMBL23117078 0.85 CRBN (0.49) CRBNDDB1
SCHEMBL24754429 0.83 DDB1 (0.47) CRBNDDB1
SCHEMBL24754425 0.82 DDB1 (0.46) CRBNDDB1
SCHEMBL31444139 0.82 DDB1 (0.46) CRBNDDB1
SCHEMBL31444106 0.81 CRBN (0.46) CRBNDDB1
SCHEMBL24754191 0.80 CRBN (0.53) CRBNDDB1BRD4TNFIL1B
SCHEMBL31323635 0.80 DDB1 (0.45) CRBNDDB1
SCHEMBL24302302 0.79 DDB1 (0.49) CRBNDDB1TNFIL1BTBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed