Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ME3 | Q16798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671496 | 0.85 | DDB1 (0.56) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL29794453 | 0.84 | DDB1 (0.50) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL25504627 | 0.81 | DDB1 (0.47) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL30694209 | 0.81 | NOTUM (0.58) | CRBNDDB1NOTUM | |
| SCHEMBL30694156 | 0.81 | NOTUM (0.58) | CRBNDDB1NOTUM | |
| SCHEMBL25193821 | 0.80 | DDB1 (0.49) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL25416997 | 0.79 | DDB1 (0.49) | CRBNDDB1ALDH1A1MAPTNOTUM | |
| SCHEMBL25818095 | 0.79 | DDB1 (0.48) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL25504703 | 0.79 | DDB1 (0.45) | CRBNDDB1ALDH1A1KDM4EHPGD | |
| SCHEMBL29096730 | 0.79 | DDB1 (0.50) | CRBNDDB1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |