Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255500 | 0.90 | TLR7 (0.39) | DYRK1ATLR7STING1BRD4CYP3A4 | |
| SCHEMBL30484354 | 0.90 | TLR7 (0.39) | DYRK1ATLR7STING1BRD4CYP3A4 | |
| SCHEMBL25818232 | 0.86 | TLR7 (0.40) | DYRK1ATLR7STING1BRD4TP53 | |
| SCHEMBL25302351 | 0.83 | TLR7 (0.41) | DYRK1ATLR7STING1BRD4CYP3A4 | |
| SCHEMBL30586090 | 0.83 | TLR7 (0.41) | DYRK1ATLR7STING1BRD4CYP3A4 | |
| SCHEMBL25303757 | 0.78 | TLR7 (0.41) | TLR7STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25297292 | 0.78 | TLR7 (0.55) | TLR7 | |
| SCHEMBL30484371 | 0.78 | TLR7 (0.41) | TLR7STING1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25256105 | 0.76 | TLR7 (0.40) | DYRK1ATLR7STING1CYP3A4CYP2D6 | |
| SCHEMBL25962881 | 0.74 | TLR7 (0.49) | TLR7TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |