Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30484371 | 0.90 | TLR7 (0.41) | TLR7LMNAGAAHTTTP53 | |
| SCHEMBL25303757 | 0.90 | TLR7 (0.41) | TLR7LMNAGAAHTTTP53 | |
| SCHEMBL25818163 | 0.86 | DYRK1A (0.39) | TLR7LMNADYRK1ATP53SMN1; SMN2 | |
| SCHEMBL31025950 | 0.83 | TLR7 (0.45) | TLR7LMNAGAAHTTTP53 | |
| SCHEMBL25258118 | 0.83 | TLR7 (0.45) | TLR7LMNAGAAHTTTP53 | |
| SCHEMBL31270997 | 0.83 | STING1 (0.38) | DYRK1ABRD4STING1 | |
| SCHEMBL25259439 | 0.83 | STING1 (0.38) | DYRK1ABRD4STING1 | |
| SCHEMBL25302704 | 0.80 | TLR8 (0.41) | TLR7DYRK1ABRD4STING1 | |
| SCHEMBL31270716 | 0.80 | TLR8 (0.41) | TLR7DYRK1ABRD4STING1 | |
| SCHEMBL25296984 | 0.78 | TLR7 (0.67) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |