SCHEMBL258183

SCHEMBL258183

C=Cc1ccc(C=C)c(C=C)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.39
TRPA1 O75762 1/20 0.39
TYMS P04818 1/20 0.39
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
HDAC8 Q9BY41 2/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
ESRRB O95718 1/20 0.32
ESRRA P11474 1/20 0.32
LRRK2 Q5S007 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415624 1.00 ALDH1A1 (0.53) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL17628515 0.97 ALDH1A1 (0.58) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL31511495 0.85 ALDH1A1 (0.43) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL9798193 0.82 ALDH1A1 (0.43) ALDH1A1TDP1TSHRMAPT
SCHEMBL27453293 0.82 ALDH1A1 (0.40) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL78055 0.79 ALDH1A1 (0.48) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL26456908 0.77 ALDH1A1 (0.46) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL2439383 0.77 ALDH1A1 (0.50) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL14135594 0.77 ALDH1A1 (0.46) ALDH1A1TDP1TP53TSHRTRPA1
SCHEMBL22964718 0.77 ALDH1A1 (0.50) ALDH1A1TDP1TP53TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3239187-B1 PROCESS FOR PRODUCING AROMATIC VINYL/CONJUGATED DIENE COPOLYMER AND PRODUCT OF HYDROGENATION THEREOF KURARAY CO (JP) 2024-09-04 EP claimed
CN-115197380-B Preparation method and application of magnetic beads for nucleic acid fragment sorting 北京迈佳致和科技有限公司 2023-11-21 CN claimed
CN-115197380-A Preparation method and application of magnetic beads for nucleic acid fragment separation 北京迈佳致和科技有限公司 2022-10-18 CN claimed
CN-109563195-B Process for producing branched modified rubber, rubber composition comprising branched modified rubber prepared by the process, and use thereof 公共型股份公司希布尔控股 2021-07-27 CN claimed
CN-109776358-B Polyalkenyl aryl isocyanate and preparation method and application thereof 万华化学集团股份有限公司 2021-05-14 CN claimed
CN-107207655-B The modified polymer based on conjugated diene, preparation method and the rubber composition comprising it LG化学株式会社 2019-11-08 CN claimed
CN-110391396-A For the composite membrane of secondary cell, preparation method and including its secondary cell 三星电子株式会社 2019-10-29 CN claimed
US-10414841-B2 Modified conjugated diene-based polymer, method for preparing the same and rubber composition including the same LG CHEM, LTD. (KR) 2019-09-17 US claimed
CN-109776358-A A kind of polyene-based aromatic isocyanate and its preparation method and application 万华化学集团股份有限公司 2019-05-21 CN claimed
CN-109563196-A Method that modified rubber is produced by anionic solution polymerization, rubber composition comprising the rubber and application thereof 公共型股份公司希布尔控股 2019-04-02 CN claimed
EP-0083575-B1 INCREASING THE REACTIVITY OF COUPLING HOMOPOLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-09-12 EP claimed
EP-0046668-B1 PROCESS FOR PRODUCING HIGH IMPACT POLYSTYRENE JAPAN ELASTOMER COMPANY LIMITED (JP) 1985-11-13 EP claimed
US-4482677-A POLYENE, ORGANOLITIUM INITIATOR, STAR POLYMERS JAPAN ELASTOMER CO., LTD. (JP) 1984-11-13 US claimed
US-4452952-A LIVING POLYMERS OF CONJUGATED DIENE, POLYVINYL AROMATIC COMPOUND AND ORGANOLITHIUM CATALYST IN POLAR SOLVENTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1984-06-05 US claimed
US-4399260-A CONJUGATED POLYENE, POLYVINYLAROMATIC COUPLER, LITHIUM-CAPPED STYRENE POLYMER, POLR COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-08-16 US claimed
EP-0083575-A1 Increasing the reactivity of coupling homopolymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-13 EP claimed
EP-0083576-A2 Increasing the reactivity of coupling of block polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-13 EP claimed
EP-0046668-A2 Process for producing high impact polystyrene JAPAN ELASTOMER COMPANY LIMITED (JP) 1982-03-03 EP claimed
US-4012317-A Process for extracting urea from a solution with alkenylaromatic polymers with α-ketoalhydic groups RHONE-POULENC S.A. (FR) 1977-03-15 US claimed
US-3933753-A Alkenylaromatic polymers with α-ketoalhydic groups RHONE-POULENC S.A. (FR) 1976-01-20 US claimed