SCHEMBL25819341

SCHEMBL25819341

CC(C)c1ccc(Oc2ccc(C(=O)c3ccc(C(C)C)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.54
ACACA Q13085 1/20 0.54
SRD5A2 P31213 3/20 0.53
ELANE P08246 2/20 0.53
HPGD P15428 4/20 0.52
RAB9A P51151 3/20 0.52
MAPT P10636 1/20 0.52
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
BCL2 P10415 1/20 0.48
MCL1 Q07820 1/20 0.48
CYP2C9 P11712 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 2/20 0.47
PARP15 Q460N3 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194410 1.00 ACACB (0.54) ACACBACACASRD5A2ELANEHPGD
SCHEMBL19223009 0.93 PARP10 (0.53) ACACBACACASRD5A2ELANEHPGD
SCHEMBL19203156 0.93 HPGD (0.61) ACACBACACASRD5A2ELANEHPGD
SCHEMBL17306109 0.91 KMT2A (0.56) ACACBACACASRD5A2ELANEHPGD
SCHEMBL25776732 0.91 ELANE (0.50) ACACBACACASRD5A2ELANEHPGD
SCHEMBL19351066 0.88 SRD5A2 (0.53) ACACBACACASRD5A2ELANEHPGD
SCHEMBL1148332 0.87 CNR1 (0.58) SRD5A2ELANEHPGDRAB9AMAPT
SCHEMBL17306100 0.87 ACACB (0.59) ACACBACACASRD5A2ELANERXRA
SCHEMBL22311660 0.87 ACACB (0.45) ACACBACACASRD5A2ELANEHPGD
SCHEMBL9403898 0.86 RXRA (0.66) SRD5A2HPGDRAB9AMAPTRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed
US-20230220158-A1 IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY NATIONAL SCIENCE FOUNDATION 2023-07-13 US disclosed