SCHEMBL25819765

SCHEMBL25819765

CC(=O)NCc1ccc(C(=O)NC2CCC(=O)NC2=O)c(C(C)=O)c1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 20/20 0.54
DDB1 Q16531 5/20 0.50
GSPT1 P15170 2/20 0.50
BRD4 O60885 1/20 0.47
IKZF3 Q9UKT9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15850448 0.81 CRBN (0.64) CRBNDDB1GSPT1BRD4
SCHEMBL16120061 0.79 CRBN (0.72) CRBNDDB1BRD4IKZF3
SCHEMBL21751120 0.79 CRBN (0.63) CRBNDDB1GSPT1BRD4IKZF3
SCHEMBL24289493 0.77 CRBN (0.63) CRBNDDB1IKZF3
SCHEMBL21751096 0.76 CRBN (0.54) CRBNDDB1GSPT1BRD4IKZF3
SCHEMBL21769092 0.75 CRBN (0.54) CRBNDDB1GSPT1BRD4IKZF3
SCHEMBL31305131 0.75 CRBN (0.54) CRBNDDB1GSPT1BRD4IKZF3
SCHEMBL21751072 0.75 CRBN (0.50) CRBNDDB1GSPT1IKZF3
SCHEMBL21751069 0.75 CRBN (0.50) CRBNDDB1GSPT1IKZF3
SCHEMBL24474444 0.73 CRBN (0.65) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023115150-A1 BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2023-06-29 WO disclosed