Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068553 | 0.80 | TP53 (0.47) | TP53SMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL16688562 | 0.80 | TP53 (0.47) | TP53SMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL16701867 | 0.77 | TP53 (0.45) | TP53SMN1; SMN2POLBGAATSHR | |
| SCHEMBL16119875 | 0.75 | TP53 (0.58) | TP53SMN1; SMN2POLBGAATSHR | |
| SCHEMBL26537652 | 0.72 | TP53 (0.41) | TP53SMN1; SMN2POLBGAAALDH1A1 | |
| SCHEMBL24927983 | 0.71 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL21679124 | 0.71 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL31368141 | 0.71 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL14157186 | 0.71 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL16681413 | 0.71 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131868-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2023-07-13 | — | — | WO | disclosed |