Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13059432 | 0.82 | KDM4E (0.47) | GAAALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL3881237 | 0.81 | ALDH1A1 (0.47) | GAAALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL6628232 | 0.81 | KDM4E (0.46) | GAAALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL13200125 | 0.80 | CYP1A2 (0.56) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3768853 | 0.79 | KDM4E (0.45) | GAAALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL25820101 | 0.79 | PDE3B (0.44) | GAAALDH1A1HSD17B10 | |
| SCHEMBL25820075 | 0.76 | CCNC (0.42) | — | |
| SCHEMBL19983447 | 0.76 | GAA (0.48) | GAAALDH1A1KDM4EHSD17B10ATM | |
| SCHEMBL25825505 | 0.75 | SMN1; SMN2 (0.35) | KDM4EHSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2608850 | 0.75 | KDM4E (0.46) | GAAALDH1A1KDM4EHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | GAA 819/4885ALDH1A1 4541/4885KDM4E 4095/4885 |
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | GAA 1228/4885ALDH1A1 3871/4885KDM4E 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.