Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820348 | 0.91 | PDK1 (0.50) | XIAPBIRC2CYP11B1NOTUMALDH1A1 | |
| SCHEMBL17368393 | 0.88 | CYP11B1 (0.56) | CYP11B1NOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10080932 | 0.86 | NOTUM (0.63) | XIAPBIRC2CYP11B1NOTUMALDH1A1 | |
| SCHEMBL22104629 | 0.82 | XIAP (0.64) | XIAPBIRC2CYP11B1NOTUMALDH1A1 | |
| SCHEMBL20348525 | 0.82 | NOTUM (0.70) | XIAPBIRC2CYP11B1NOTUMALDH1A1 | |
| SCHEMBL21348490 | 0.80 | HPGD (0.62) | XIAPBIRC2ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL17368396 | 0.79 | PDK1 (0.62) | CYP11B1NOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25786385 | 0.78 | NOTUM (0.59) | XIAPBIRC2NOTUMALDH1A1TSHR | |
| SCHEMBL17341938 | 0.78 | TSHR (0.67) | NOTUMALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL30911970 | 0.76 | XIAP (0.54) | XIAPBIRC2NOTUMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | XIAP 722/4885BIRC2 940/4885CYP11B1 587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.