Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 11/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670531 | 0.84 | IDH1 (0.46) | DPP4NR1H2NR1H3ANPEPKMT2A | |
| SCHEMBL18368381 | 0.83 | POLB (0.48) | GRM5DPP4NR1H2NR1H3ANPEP | |
| SCHEMBL5811349 | 0.81 | PARP10 (0.44) | GRM5CNR1IDH1 | |
| SCHEMBL5808991 | 0.79 | GRM5 (0.39) | GRM5CNR1IDH1 | |
| SCHEMBL25465444 | 0.79 | GRM5 (0.39) | GRM5CNR1IDH1 | |
| SCHEMBL27049002 | 0.78 | GRM5 (0.39) | GRM5CNR1IDH1 | |
| SCHEMBL5806359 | 0.78 | GRM5 (0.41) | GRM5CNR1KMT2A | |
| SCHEMBL9914264 | 0.77 | FAAH (0.36) | CNR1KMT2A | |
| SCHEMBL31387075 | 0.77 | GRM5 (0.39) | GRM5CNR1 | |
| SCHEMBL27036982 | 0.77 | GRM5 (0.39) | GRM5CNR1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | GRM5 2844/4885DPP4 3650/4885NR1H2 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.