Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 17/20 | 0.40 |
| ▸ | HTR2B | P41595 | 16/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019941 | 1.00 | HTR2C (0.40) | HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL2017751 | 0.92 | HTR2C (0.40) | HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL2016192 | 0.84 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL2575116 | 0.84 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL2562895 | 0.84 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL2016529 | 0.84 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL2013664 | 0.84 | HTR2C (0.49) | HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL2576587 | 0.84 | HTR2C (0.49) | HTR2CHTR2BHTR2AHRH3 | |
| SCHEMBL2015345 | 0.83 | HTR2C (0.46) | HTR2CHTR2BHTR2A | |
| SCHEMBL2014311 | 0.82 | HTR2C (0.39) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560973-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbvie Inc. (US) | 2013-02-27 | — | — | EP | claimed |
| WO-2011133182-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-10-27 | — | — | WO | claimed |