Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.61 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24010292 | 0.93 | KMT2A (0.61) | SMARCA2SMARCA4KDRKMT2ASMN1; SMN2 | |
| SCHEMBL9828922 | 0.90 | SMARCA2 (0.69) | SMARCA2SMARCA4KDRMAPK1LMNA | |
| SCHEMBL30232524 | 0.87 | KCNK3 (0.55) | KMT2ATP53POLBMEN1 | |
| SCHEMBL24003834 | 0.87 | KCNK3 (0.55) | KMT2ATP53POLBMEN1 | |
| SCHEMBL30290919 | 0.87 | BRAF (0.57) | MAPTKMT2APOLBMEN1 | |
| SCHEMBL24010657 | 0.87 | BRAF (0.57) | MAPTKMT2APOLBMEN1 | |
| SCHEMBL7659797 | 0.84 | NPSR1 (0.53) | SMARCA2SMARCA4KDRMAPK1LMNA | |
| SCHEMBL31494286 | 0.84 | NPSR1 (0.53) | SMARCA2SMARCA4KDRMAPK1LMNA | |
| SCHEMBL25821628 | 0.83 | PORCN (0.55) | SMARCA2SMARCA4MAPK1LMNAMAPT | |
| SCHEMBL24003823 | 0.83 | BRAF (0.54) | KMT2ASMN1; SMN2NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | SMARCA2 2441/4885SMARCA4 1901/4885KDR 2851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.