Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.76 |
| ▸ | MEN1 | O00255 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | THRA | P10827 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.62 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16430901 | 0.94 | MEN1 (0.81) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL10943066 | 0.90 | KMT2A (0.94) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL27903466 | 0.87 | KMT2A (0.86) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL32690121 | 0.87 | MEN1 (1.00) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL18300094 | 0.87 | MEN1 (1.00) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL6155499 | 0.86 | MAPT (0.76) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL299879 | 0.85 | KMT2A (0.88) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL30868371 | 0.85 | KMT2A (0.88) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL3817483 | 0.84 | MEN1 (0.71) | KMT2AMEN1MAPTPOLBBLM | |
| SCHEMBL17409104 | 0.84 | MEN1 (0.78) | KMT2AMEN1MAPTPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
| CN-102531949-A | Substituted benzamide compounds and preparation method and application thereof | INST MATERIA MEDICA CAMS | 2012-07-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KMT2A 4131/4885MEN1 1172/4885MAPT 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.