Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.76 |
| ▸ | GAA | P10253 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25822192 | 0.86 | KMT2A (0.76) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL6154317 | 0.84 | MAPT (0.82) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL6154823 | 0.82 | ALDH1A1 (0.59) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL16430901 | 0.81 | MEN1 (0.81) | MAPTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL6154649 | 0.80 | MAPT (1.00) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL6155197 | 0.80 | GAA (0.74) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL6154198 | 0.80 | GAA (0.74) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL6155202 | 0.78 | GAA (0.71) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL30542203 | 0.77 | ALDH1A1 (0.65) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL10943066 | 0.77 | KMT2A (0.94) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | PTPRS, PTPRJ, PTPRCAP | MAPT 3318/4885GAA 2365/4885MEN1 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.