Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31093745 | 1.00 | TRPA1 (0.41) | TRPA1ATRS1PR3MAPKAPK2AAK1 | |
| SCHEMBL1699239 | 0.85 | ATR (0.46) | TRPA1ATRS1PR3MAPKAPK2METAP1 | |
| SCHEMBL21046899 | 0.84 | TRPA1 (0.42) | TRPA1ATRS1PR3MAPKAPK2METAP1 | |
| SCHEMBL31093828 | 0.84 | AAK1 (0.40) | ATRAAK1CYP17A1METAP1LCK | |
| SCHEMBL31093805 | 0.83 | CYP17A1 (0.42) | ATRAAK1CYP17A1METAP1LCK | |
| SCHEMBL12248187 | 0.82 | TRPA1 (0.41) | TRPA1ATRS1PR3MAPKAPK2METAP1 | |
| SCHEMBL31093842 | 0.82 | LCK (0.38) | ATRAAK1CYP17A1METAP1LCK | |
| SCHEMBL31093807 | 0.81 | RXFP1 (0.46) | AAK1CYP17A1METAP1 | |
| SCHEMBL24157078 | 0.78 | ATR (0.42) | TRPA1ATRMAPKAPK2AAK1METAP1 | |
| SCHEMBL31493121 | 0.78 | ATR (0.42) | TRPA1ATRMAPKAPK2AAK1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133413-A1 | MULTICYCLIC COMPOUNDS | SLAP PHARMACEUTICALS LLC (US) | 2023-07-13 | — | — | WO | disclosed |