SCHEMBL25822397

SCHEMBL25822397

COCOc1cc(B2OC(C)(C)C(C)(C)O2)c2c(CCF)cccc2c1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.32
LIPG Q9Y5X9 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25824424 0.91 LPL (0.33) LPLLIPG
SCHEMBL29418723 0.87 LPL (0.33) LPLLIPG
SCHEMBL23043415 0.87 LPL (0.33) LPLLIPG
SCHEMBL26197307 0.84 LPL (0.34) LPLLIPG
SCHEMBL29913820 0.84 LPL (0.34) LPLLIPG
SCHEMBL30960000 0.82 LPL (0.35) LPLLIPG
SCHEMBL30124102 0.82 LPL (0.35) LPLLIPG
SCHEMBL23043299 0.82 LPL (0.35) LPLLIPG
SCHEMBL25426937 0.82 LPL (0.35) LPLLIPG
SCHEMBL30922681 0.82 RPS6KB2 (0.33) LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125989-A1 QUINAZOLINE COMPOUND AND APPLICATION THEREOF 上海医药集团股份有限公司 2023-07-06 WO disclosed