Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13382259 | 0.87 | DPP4 (0.40) | DPP4DRD2DRD4DRD3MEN1 | |
| SCHEMBL15976246 | 0.86 | GBA1 (0.47) | DPP4DRD2DRD4DRD3NAMPT | |
| SCHEMBL15976247 | 0.86 | GBA1 (0.47) | DPP4DRD2DRD4DRD3NAMPT | |
| SCHEMBL13469511 | 0.85 | SMPD1 (0.44) | DPP4DRD2DRD4DRD3GBA1 | |
| SCHEMBL15281111 | 0.84 | CHRNA7 (0.38) | DPP4DRD2DRD4DRD3DGAT1 | |
| SCHEMBL18850692 | 0.84 | CHRNA7 (0.38) | DPP4DRD2DRD4DRD3DGAT1 | |
| SCHEMBL17586038 | 0.84 | CHRNA7 (0.38) | DPP4DRD2DRD4DRD3DGAT1 | |
| SCHEMBL15223677 | 0.84 | CHRNA7 (0.38) | DPP4DRD2DRD4DRD3DGAT1 | |
| SCHEMBL15976248 | 0.80 | GBA1 (0.39) | DPP4DRD2DRD4DRD3GBA1 | |
| SCHEMBL16526395 | 0.79 | SMPD1 (0.51) | DRD2DRD4DRD3GBA1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |