Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25250931 | 0.99 | PLA2G4B (0.48) | PLA2G4BPPARGPPARACFDPLAU | |
| Hydrochloric Acid SCHEMBL25292291 | 0.89 | PPARA (0.52) | PLA2G4BPPARGPPARAPPARDFFAR1 | |
| SCHEMBL24675498 | 0.87 | CNR1 (0.47) | PLA2G4BPPARACFDFFAR1HDAC1 | |
| SCHEMBL24675243 | 0.87 | PLA2G4B (0.46) | PLA2G4BPPARGPPARACFDFFAR1 | |
| SCHEMBL25823611 | 0.87 | POLB (0.56) | PLA2G4BPPARGPPARAPOLB | |
| SCHEMBL24675917 | 0.86 | PLA2G4B (0.48) | PLA2G4BFFAR1HDAC1HDAC2CYP4F2 | |
| SCHEMBL24675114 | 0.86 | PLA2G4B (0.44) | PLA2G4BPPARGPPARAPOLB | |
| Hydrochloric Acid SCHEMBL25298667 | 0.86 | PPARA (0.52) | PLA2G4BPPARGPPARA | |
| Hydrochloric Acid SCHEMBL25290504 | 0.86 | PLA2G4B (0.46) | PLA2G4BPPARGPPARACFDFFAR1 | |
| Hydrochloric Acid SCHEMBL27225814 | 0.86 | CNR1 (0.47) | PLA2G4BPPARACFDFFAR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129564-A9 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2024-02-08 | — | — | WO | disclosed |
| WO-2023129564-A1 | DEGRADERS OF GRK2 AND USES THEREOF | CYGNAL THERAPEUTICS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |